Organ Rejection and Its Management

Organ rejection occurs when the body’s immune system identifies a transplanted organ as a foreign invader and attacks it. This reaction happens because the immune system recognizes the new organ as different from the body’s natural tissues, triggering an immune response that can damage or destroy the organ.

Treatments for organ rejection include increasing doses of immunosuppressive medications, administering high doses of steroids to reduce inflammation, and in severe cases, using treatments like plasma exchange to remove harmful antibodies. The goal is to control the immune system’s response and protect the transplanted organ.

Preventing organ rejection involves taking immunosuppressive medications as prescribed, attending regular medical check-ups, maintaining a healthy lifestyle, practicing good hygiene to avoid infections, and adhering to a balanced diet and exercise routine.

Several factors can contribute to organ rejection, including tissue mismatch between the donor and recipient, not following the prescribed medication regimen, infections that weaken the immune system, and pre-existing medical conditions.

Organ rejection is classified mainly into two types: acute rejection, which happens within the first few months after a transplant, and chronic rejection, which develops slowly over time, sometimes taking years. Each type requires different treatment and monitoring strategies.